Extended Time of Cold Ischemia and Its Influence on the Physiological Function of Human Adult Pancreatic Islets

نویسندگان

  • D. M. NIKOLIĆ
  • P. B. DJORDJEVIĆ
  • Đ. RADAK
  • VESNA B. LAČKOVIĆ
  • MILOŠ I. BAJČETIĆ
  • GORDANA MILIĆ
  • D. GOSTILJAC
  • M. ILIĆ
  • NEVENKA RAKETIĆ
  • VESNA STOJILJKOVIC
  • NIKICA M. GRUBOR
  • M. D. JOVANOVIĆ
  • S. M. LATINČIĆ
چکیده

In this study we compared the effects of duration of cold ischemia (longer and shorter ischemia) on the yield, viability and preservation of the physiological function and insulin secretion of adult human pancreatic islets in short-term (seven days) culture. Based on the tested parameters, we established that there are no major differences between these two test groups and that the storage and transport of pancreatic tissue in physiological solution at 4oC gives quite satisfactory results.

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تاریخ انتشار 2011